Detalhe da pesquisa
1.
Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities.
Med Res Rev
; 40(6): 2177-2211, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32588916
2.
N-Acylhydrazones as drugs.
Bioorg Med Chem Lett
; 28(17): 2797-2806, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30006065
3.
Click-Capable Phenanthriplatin Derivatives as Tools to Study Pt(II)-Induced Nucleolar Stress.
ACS Chem Biol
; 19(4): 875-885, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483263
4.
First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins.
Chem Commun (Camb)
; 59(84): 12641-12644, 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37791917
5.
Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC.
J Thorac Oncol
; 18(7): 882-895, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36958689
6.
Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol-3-kinase (PI3K): Current and Future Prospects.
ChemMedChem
; 16(3): 448-457, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049098
7.
Determination of rare earth elements in Fe-minerals using external calibration by LA-ICP-MS and application on Cauê Iron Formation (Brazil).
Talanta
; 219: 121239, 2020 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32887130
8.
Design, Synthesis, and Pharmacological Evaluation of First-in-Class Multitarget N-Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors.
ChemMedChem
; 15(6): 539-551, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32022441
9.
Duvelisib: A 2018 Novel FDA-Approved Small Molecule Inhibiting Phosphoinositide 3-Kinases.
Pharmaceuticals (Basel)
; 12(2)2019 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31064155
10.
The Use of Conformational Restriction in Medicinal Chemistry.
Curr Top Med Chem
; 19(19): 1712-1733, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31659944
11.
Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
J Med Chem
; 61(14): 5805-5821, 2018 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29446940
12.
Beyond the Selective Inhibition of Histone Deacetylase 6.
Mini Rev Med Chem
; 16(14): 1175-84, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27121714
13.
Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.
J Med Chem
; 59(2): 655-70, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26705137
14.
Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.
Eur J Med Chem
; 62: 214-21, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23353740
15.